Multiple sequence alignments of the MDS00105 motif region. The proteins are designated by the species abbreviation and the name. The positions of motif MDS00105 are indicated by “+”. Submotif positions based on regular expressions are designated by “#&”. Multiple sequence alignments of representative complete sequences are shown in Supplement Figure 1A,B,C. (A) Alignment ING1 and ING1L MDS00105.1 motif region. The SWISS-PROT/TrEMBL accessions of the sequences are as follows: (HSA)P47ING1, Q9UIJ4; (HSA)P33ING1A, O43658; (MMU)Ing1 [isoform 1], Q9QXV3 isoform 1; (HSA)P47ING1A, Q9UK53; (HSA)P24ING1B, Q9UBC6; (HSA)ING1C, Q9P0U6; (HSA)P33ING1B [fragment]; CAC38067; (HSA)P33ING1, O00532; (HSA)P24ING1C, Q9NS8; (HSA)P33ING1, Q9UIJ2; (HSA)P33ING1B, Q9UK52; (HSA)ING1 [isoform], Q9H007; (HSA)ING1, Q9HD98; (HSA)ING1 [fragment], Q9HD99; (HSA)ING2, Q9H160; (HSA)ING1L,O95698; (MMU)Ing2, Q9ESK4; (MMU)2810011M06Rik, Q9CZD8; and (DMEL)CG7379, Q9VEF5. (B) Alignment of ING1 homolog MDS00105.2 motif region. The SWISS-PROT/TrEMBL accessions of the ING1 homolog sequences are as follows: (HSA)LOC51147 [P33ING1 homolog], Q9UNL4; (HSA)MY036, Q9H3J0; (HSA)MGC12557, AAH07781; (HSA)MGC4757 [similar to (MMU)1700027H23Rik], AAH13038; (HSA)MGC12080, AAH09127; (MMU)D6Wsu147e, Q9D7F9; (MMU)D6Wsu147e [variant]; (MMU)1810018M11Rik, Q9D8Y8; (MMU)1810018M11Rik [partial]; (MMU)1700027H23Rik, Q9D9V8; (HSA)MGC12485 [similar to (MMU)1819918M11Rik], Q9BS30; (DMEL)CG9293, Q9VJY8; (SPOM)C3G9.08, O42871; (ATHA)14013, Q9LIQ6; and (ATHA)F20D21.22, Q9SLJ4. (C) Alignment of the ING3 MDS00105.3 motif region. The SWISS-PROT/TrEMBL accessions of the other ING3 subfamily sequences are as follows: (HSA)P47ING3 [variant 1], Q9NXR8; (HSA)P47ING3 [variant 2], Q9HC99; (HSA)ING3, O60394; (MMU)p47Ing3, Q9ERB2; (MMU)13000 13A07Rik, Q9DBG0; (HSA)DKFZp586C1218, CAC48260; and (DMEL)CG6632, Q9VWS0.
