The Evolution of DNA Regulatory Regions for Proteo-Gamma Bacteria by Interspecies Comparisons

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Figure 2.
Figure 2.

The probability profiles for the orthologous region upstream of the gene lpdA (lipoamide dehydrognease (NADH). The abscissa is in bp units, and the start codon for lpdA begins at position 325. In (a), κ = 0 for all species, whereas in (b) it is optimized separately in each case (as explained in the text), which yields κ = 0.006, 0.003, 0.01, and 0.06 for kpn, stm, vch, and ype, respectively. The two known factor binding sites for sigma 70 (rpoD17) and an anaerobic factor arcA are marked. In (b), the predictions of McCue et al. (2001) are marked with “W” and the remaining bars are our predictions from the summed profiles.

This Article

  1. Genome Res. 12: 298-308

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