Control Genes and Variability: Absence of Ubiquitous Reference Transcripts in Diverse Mammalian Expression Studies

Table 2.

Genes identified by filtering with CV less than 0.7 across all four datasets

Gene Description NC160 AML/ALL Huge index TPA
MFC CV MFC CV MFC CV MFC CV
RPS27A Ribosomal protein S27a 2.2 0.17 3.2 0.19 3.1 0.37 5.6 0.61
RPL19 Ribosomal protein L19 3.2 0.24 2.6 0.19 2 0.21 2.6 0.29
HSPCA Heat shock 90kD protein 1, alpha 9.8 0.25 7.7 0.44 7.3 0.47 4.8 0.32
RPL11 Ribosomal protein L11 3.4 0.25 3.8 0.2 2.8 0.3 11.8 0.54
RPS29 Ribosomal protein S29 3.1 0.26 4.2 0.25 1.6 0.16 3.3 0.33
NONO Non-POU-domain-containing, octamer-binding 4 0.28 3.7 0.25 1.4 0.1 4.3 0.33
AAMP Angio-associated migratory cell protein 4 0.31 8.4 0.34 2.2 0.31 4.2 0.43
RPS3 Ribosomal protein S3 4.2 0.32 3.5 0.24 3.9 0.35 2.7 0.26
ARHGDIA Rho GDP dissociation inhibitor (GDI) alpha 7.6 0.38 7 0.29 1.4 0.15 3.8 0.31
  • CV, coefficient of variation; MFC, maximum fold change; AML/ALL, acute myeloid leukemia/acute lymphoblastic leukemia panels; TPA, phorbol 12-myristate 13-acetate induction.

This Article

  1. Genome Res. 12: 292-297

Preprint Server