Protein–Protein Interactions Between Large Proteins: Two-Hybrid Screening Using a Functionally Classified Library Composed of Long cDNAs

Table 2.

Protein-Protein Interaction Pairs Between Large Proteins

Bait Description Prey Description
KIAA0319 KIAA0396(2) FEM-1-like death receptor-binding protein
KIAA1299(1) SH2-B β-signaling protein
KIAA0343 KIAA0417(2)
KIAA1251(1) Trabeculin-α
KIAA1634(6) Membrane-associated guanylate kinease-related MAGI-3
KIAA0348 Synaptojanin 2 KIAA1256(3) Intersectin 2 (SH3D1B)
KIAA0358 MAP kinase-activating death domain protein KIAA0453(1)
KIAA0364 Immunoglobulin-like domain-containing 1 protein KIAA1131(1)
KIAA1464(1) RanBPM homolog (66%)
KIAA0387 Protein-tyrosine phosphatase X precursor KIAA0097(2) CH-TOG PROTEIN
KIAA0463 Plexin 2 precursor KIAA0144(1)
KIAA1014(1) Formin-binding protein 30
KIAA1199(1)
KIAA1374(1)
KIAA0543 KIAA1043(1)
KIAA1218(1)
KIAA0578 Neurexin I-α KIAA0300(1) PDZ domain-containing protein AIPC
KIAA0440(1) High-risk human papilloma viruses E6 oncoproteins targeted protein E6TP1 α
KIAA0865(1)
KIAA1251(2) Trabeculin-α
KIAA0603 KIAA0332(2)
KIAA0765(2) RNA binding motif protein 12
KIAA1498(2) p400 SWI2/SNF2-related protein
KIAA1546(2)
KIAA0620 KIAA1251(1) Trabeculin-α
KIAA0690 KIAA0109(1) Clathrin coat assembly protein AP50
KIAA0812 MEGF2/Flamingo KIAA0640(9) SWAP-70 homolog
KIAA0728(3) Bullous pemphigoid antigen 1-a (Bpag1)
KIAA0816 MEGF7 KIAA1526(2)
KIAA0868 Contactin associated protein-like 2 (Caspr2) KIAA0155(10) TPR-containing/SH2-binding phosphoprotein
KIAA1224(1)
KIAA1251(2) Trabeculin-α
KIAA0911 Calsyntenin-1 KIAA0045(2) Thyroid hormone receptor interactor 12
KIAA0067(1) ERG-associated protein ESET
KIAA0204(3) CTCL tumor antigen se20-9
KIAA0572(2) 80-kDa MCM3-associated protein
KIAA1447(3)
KIAA0921 Neurexin 2-α KIAA1251(1) Trabeculin-α
KIAA0960 KIAA0400(3)
KIAA0987 Band 4.1-like protein 3 KIAA0912(1)
KIAA1032(2) Munc13–1
KIAA1062 ATP-binding cassette, sub-family A KIAA1633(5)
KIAA1132 KIAA0705(8) Synaptic scaffolding protein S-SCAM
KIAA1092(2) PLC-L2 mRNA for phospholipase C-L2
KIAA1634(14) Membrane-associated guanylate kinase-related MAGI-3
KIAA1206 Plexin-B3 (PLXNB3) KIAA0076(3)
KIAA0275(1) Testican-2
KIAA0380(5) RhoGEF glutamate transport modulator GTRAP48
KIAA0705(1) Synaptic scaffolding protein S-SCAM
KIAA0708(1) KIAA0076 homolog (62%)
KIAA0952(1)
KIAA1634(3) Membrane-associated guanylate kinase-related MAGI-3
KIAA1216 Vitamin D3 receptor interacting protein KIAA0235(1) Pumilio 2
KIAA0593(1) Thyroid hormone receptor-associated protein complex component TRAP240
KIAA1037(1)
KIAA1041(1)
KIAA1278 FUSED serine/threonine kinase KIAA0316(2)
KIAA0807(3) Microtubule-associated serine/threonine protein kinase
KIAA1633(1)
KIAA1368 Semaphorin 6A KIAA0777(1) SH3-containing protein p4015
KIAA1256(1) Intersectin 2 (SH3D1B)
KIAA1296(6) R85FL
KIAA1494(6) SH3 domains-containing protein POSH
KIAA1394 KIAA0045(4) Thyroid hormone receptor interactor 12
KIAA1549 KIAA0728(1) Bullous pemphigoid antigen 1-a
KIAA1119(1) MYOSIN VB
KIAA1121(1) Calcium-dependent actin-binding protein
KIAA1256(1) Intersectin 2 (SH3D1B)
KIAA1461(1)
KIAA1573 KIAA0240(1)
KIAA1177(2) HCNP protein; XPA-binding protein 2
KIAA1224(2)
KIAA1464(1) RanBPM homolog (66%)
KIAA1679 KIAA1464(5) RanBPM homolog (66%)
KIAA1746 KIAA0465(1) Actin binding protein ABP620
KIAA1763 CASPR4 KIAA0561(1) Microtubule- and syntrophin-associated serine–threonine protein kinase homolog (63%)
KIAA0875(1) F-box only protein 21
KIAA1251(1) Trabeculin-α
KIAA1464(8) RanBPM homolog (66%)
KIAA1780 MEGF10 KIAA0109(5) Clathrin coat assembly protein AP50
KIAA0207(2) Growth factor receptor-bound protein 10
KIAA0577(2) Putative pre-mRNA splicing factor RNA helicase
KIAA0788(2) U5 small nuclear ribonucleoprotein 200 kDa helicase
KIAA1464(2) RanBPM homolog (66%)
  • The number in parentheses represents the number of independent, isolated, positive clones.

  • Homologous genes whose sequences are more than 80% identified are detailed in the description column. Concerning annotation worth being described but lower than 80% identity, the percent identity is given in parentheses.

  • When 10 or more preys were identified, only preys prepared from two or more independent clones were listed because the bait may contain a sticky region.

  • All interaction data in this report are available in the public database BIND (BIND ID 12487–12570; http://www.bind.ca).

This Article

  1. Genome Res. 12: 1773-1784

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