Signatures of Domain Shuffling in the Human Genome

Table 8.

Observed and Expected Numbers of Old and New Domains and Families inC. elegans Genes That Are Bounded Symmetrically by Phase 0, Phase 1, or Phase 2 Introns

New Old
Domain (40) Family (19) Domain (134) Family (52)
Obs. Exp. P Obs. Exp. P Obs. Exp. P Obs. Exp. P
0–0 1 7 0.01 1 3.9 n.d. 29 24.7 0.34 12.1 10.7 0.63
1–1 23 11.4 <10−4 6.1 2.6 n.d. 8 27.3 <10−4 3.4 7.2 0.13
2–2 0 2.1 n.d. 0 1.3 n.d. 7 7 1 3.3 3.5 n.d.
  • Total numbers of domains in each category are indicated in parentheses. Some P-values were not determined (n.d.) due to the low sample size. (Obs.) Observed; (Exp.) Expected.

This Article

  1. Genome Res. 12: 1642-1650

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