Inferring Domain–Domain Interactions From Protein–Protein Interactions

Table 3.

Summary Statistics of Distribution of the Correlation Coefficient Between the Expression Profiles of Two Interacting Proteins (With Gene Expression Profiles From Different Data Sets and Predictions (fp = 2.5E-4, fn = 0.80) With Different Probability Thresholds

Pairs Pairs Mean Std T-score P value
All ORFs 3036880 0.0410 0.2444 0.0000 5.000e-01
≥0.20 5333 0.0657 0.2529 7.3985 7.186e-14
≥0.40 3692 0.0774 0.2549 9.0661 6.541e-20
≥0.60 2764 0.0858 0.2613 9.6445 2.766e-22
≥0.80 2205 0.0832 0.2609 8.1043 2.788e-16
≥0.975 1959 0.0841 0.2628 7.8134 2.917e-15
Uetz + Ito 1307 0.0841 0.2600 6.3775 9.292e-11
MIPS 1100 0.1646 0.2721 16.8504 5.860e-64

This Article

  1. Genome Res. 12: 1540-1548

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