Inferring Domain–Domain Interactions From Protein–Protein Interactions

Table 2.

Number of Matched Protein Pairs Between the Predictions

Threshold Prediction Train MIPS MIPS1 Fold Z score P value
All 20221620 5719 2575 1417 1
>0.00 125435 5717 1263 106 12.63 33.70 3.88e-249
≥0.20 23182 5154 1074 51 40.36 44.25
≥0.40 16287 4847 993 47 58.61 51.59
≥0.60 12748 4647 933 43 75.73 56.31
≥0.80 10441 4437 882 40 95.05 61.01
≥0.975 9413 4289 845 35 97.45 57.80
  • (Prediction) fp = 2.5E-4, fn = 0.80, the training set (Train), the MIPS data (MIPS), and the MIPS excluding the training data (MIPS1), respectively. The corresponding statistics (Fold, Z score, and P value) are also given.

This Article

  1. Genome Res. 12: 1540-1548

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