Molecular Characterization of a Chromosomal Rearrangement Involved in the Adaptive Evolution of Yeast Strains

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Figure 2.
Figure 2.

Diagrams representing the organization of the ECM34 (in gray) and SSU1 (in black) nonrecombinant alleles and their corresponding recombinant variants obtained by an illegitimate crossing-over of a microhomology region (see Fig. 3), indicated by a vertical line, located in the promoters of both genes. This illegitimate crossing-over was involved in the generation of the reciprocal translocation between chromosomes VIII and XVI found inSaccharomyces strains (Fig. 1). Thick arrows represent the protein-coding regions of each gene. The pentagon block corresponds to a 76-bp sequence that has been found several times repeated in the promoters of both nonrecombinant ECM34 (strain CECT 1477) and recombinant SSU1-R (several strains). Strains bearing these sequences are indicated for each diagram.

This Article

  1. Genome Res. 12: 1533-1539

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