Factors Influencing the Identification of Transcription Factor Binding Sites by Cross-Species Comparison

Table 5.

Study Set Results at Different P Values

Quantile Number of motif predictions Motif predictions with avg MAP ≥ critical value Correspondence with known sites for:
Motif predictions with avg MAP ≥ critical value Motif predictions with avg MAP < critical value
80% (P = 0.20) 163 129 93 19
90% (P = 0.10) 163 108 81 31
95% (P = 0.05) 163 85 64 48
99% (P = 0.01) 163 50 37 75
  • Using orthologous data sets containingEscherichia coli–Salmonella typhi–Yersinia pestis–Vibrio cholerae–Haemophilus influenzae–Shewanella oneidensis–Pseudomonas aeruginosa and analyzing motif predictions that contain sites from at least two species.

This Article

  1. Genome Res. 12: 1523-1532

Preprint Server