Identification and Analysis of Over 2000 Ribosomal Protein Pseudogenes in the Human Genome

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Figure 7.
Figure 7.

Amino acid sequence alignment of RPL26 genes from yeast, worm, fruit fly, rat, and human, and a processed pseudogene (chr16_RL26_5) found in the intron region of the human functional RPS2 gene. The residues highlighted in gray are those present in the pseudogene and also in both the mammalian and invertebrate proteins; the residues outlined in bold are those present in the pseudogene and the mammals but not in invertebrates. In the pseudogene sequence, * represents a stop codon, and an underscored amino acid indicates an adjacent frame shift. Rat and human RPL26 have almost identical sequences except at position 100, where the rat protein and the pseudogene have an Arginine and human protein has a Histidine.

This Article

  1. Genome Res. 12: 1466-1482

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