Human Paralogs of KIAA0187 Were Created through Independent Pericentromeric-Directed and Chromosome-Specific Duplication Mechanisms

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Figure 3.
Figure 3.

Phylogenetic analysis of KIAA0187 paralogs. The scale for branch lengths is shown, and nodes with >50% bootstrap support are indicated. (A) Maximum-likelihood tree of distal paralogs. Derived from an 1892-bp alignment spanning positions 694294–696183 of the 10q11 sequence (Guy et al. 2000), which contains no exonic sequence. The chromosomal assignment for each clone is shown in brackets. (B) Maximum-likelihood tree of proximal paralogs. Derived from a 1909-bp alignment spanning positions 666815–668710 of the 10q11 sequence (Guy et al. 2000), which contains 235 bp of exonic sequence. The map position on chromosome 10 is shown for each sequence.

This Article

  1. Genome Res. 12: 67-80

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