Figure 2.
Domain architecture of proteins containing the SPK domain. Only proteins with distinct modular organizations are shown. The domain names are those of the Simple Modular Architecture Research Tool (http://smart.embl-heidelberg.de) (Schultz et al. 1998, 2000). CASc, catalytic domain of caspases; PHD, PHD C4HC3 zinc finger; SET, (Su(var)3–9, Enhancer-of-zeste, Trithorax) domain; STYKc, catalytic domain of protein kinases. The UCH-2 (ubiquitin carboxy-terminal hydrolase family 2) domain is defined by Pfam (Bateman et al. 2000)
