
Detection of chimeric reads. Reads l 1,l 2, l 3, r 1,r 2, and r 3, and the absence of a read n (having long overlaps on both sides of a pointx) suggest that read c may be chimeric, consisting of the juxtaposition of two disparate genomic segments: one corresponding to the part of c before x, and one corresponding to the part of c after x. We call x thepoint of chimerism of c. Note that readsl 3 and r 3 extend slightly beyondx, as often happens for real chimeric reads.











