Enzymatic Regional Methylation Assay: A Novel Method to Quantify Regional CpG Methylation Density

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Figure 2.
Figure 2.

Mixing experiments using DNA form the cell lines KG1a and HL60. The ratio (3H/14C signal) is plotted against the percentage of KG1a DNA in the mixtures. The graph shows a linear relation between p15INK4B promoter methylation density and the ratio (3H/14C signal). Results are expressed as the mean value ± SD of triplicates (correlation coefficient = 0.99).

This Article

  1. Published in Advance December 14, 2001, doi: 10.1101/gr.202501 Genome Res. 12: 153-157

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