Flexible Use of High-Density Oligonucleotide Arrays for Single-Nucleotide Polymorphism Discovery and Validation

Table 1.

Summary of SNP Screening and Validation by Gel-Based Sequencing

Chromosome	Number of selected fragments	Number of SNPs	Number of SNPs tested by gel sequencing	Number of SNPs confirmed by gel sequencing
1	43	8	6	4
2	3	0	0	0
3	0	0	0	0
4	20	2	2	2
5	56	9	6	4
6	79	19	15	14
7	152	27	19	18
8	7	1	1	1
9	2	1	0	0
10	3	1	1	1
11	4	0	0	0
12	29	2	2	2
13	7	0	0	0
14	6	1	1	1
15	0	0	0	0
16	29	5	4	2
17	40	5	4	3
18	1	0	0	0
19	0	0	0	0
20	13	5	5	4
21	4	0	0	0
22	34	10	8	6
X	174	27	17	14
Y	0	0	0	0
Unknown origin	7	1	1	1
Total	713	124	92	88

Published in Advance July 12, 2001, doi: 10.1101/gr.171101 Genome Res. 2001. 11: 1418-1424

Flexible Use of High-Density Oligonucleotide Arrays for Single-Nucleotide Polymorphism Discovery and Validation