Capturing Whole-Genome Characteristics in Short Sequences Using a Naïve Bayesian Classifier

Table 1.

List of Putative Horizontally Transferred Genes

Gene ORF Classification (kb) BLAST BLASTX HmUS
SodC NMB1398/NMA1617 1/1 M84012(E = 0.0; 87%) M84012 (E = 4e-95)             28/29 ‖ 28/29
bio gene cluster -bioC NMB0474/NMA2011 0.75/1.5 U32830 (E = 0.0; 88%) P45248 (E = 1e-134)             29/29 ‖ 29/29
Conserved hypothetical protein NMB1979/NMA0465 1.25/1.25 U32837 (E = 0.0; 92%) HI1643 (E = 3e-158)             28/29 ‖ 27/29
Type III restriction enzyme CA09003/NMA1591 2.75/3.5 U32786 (E = 0.0; 92%) HI1055 (E = 0.0)             28/29 ‖ 27/29
Type III methyltransferase —/NMA1590 0.5/0.5 U32786(E = 0.0; 92%) HI1056 (E = 0.0)             28/29 ‖ 27/29
Virulence associated protein U23782/NMA1725 1.75/1.25 U32728 (E = 2e-45; 95%) 2 * 29/29 ‖ 2 * 29/29
  • Genes identified as horizontally transferred from Haemophilus influenzae to Neisseria meningitis. ORF and Bayesian classification data are provided for both N. meningitisserotype A and, in parentheses for serotype B. Classification column indicates block length identified as being of H. influenzaeorigin. The genomic regions identified in N. meningitis were compared for homology using BLAST toward H. influenzae and the homologous sequences reported with accession number,e-value and percent identical nucleotides. The best hit after searching genomic regions using BLASTX with accession number and e-value. HmUS indicates the number of perfect matching nucleotides between the N. meningitis region and the consensus. The two N. meningitis genomes gave almost identical results (data not shown).

  • Putative horizontal gene transfer events identified by another study (Kroll et al. 1998).

This Article

  1. Genome Res. 11: 1404-1409

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