High-Throughput Genotyping with Single Nucleotide Polymorphisms

Table 2.

Radiation Hybrid Analysis

SNP Allele 1, but not Allele 2, positive Allele 2, but not Allele 1, positive Allele 1 and Allele 2 positive Polymorphic
WIAF2065 17 13 2 yes
WIASF896 22 22 5 yes
WIAF610 15 9 2 yes
WIAF2042 11 15 0 yes
WIAF1161 0 0 35 no
WIAF2566 0 0 28 no
WIAF335 0 0 38 no
  • The number of radiation-hybrid cell-lines scoring positive on the Genebridge 4 panel is given. Cell-lines were typed using the TaqMan assay and scored by comparing the signal to that obtained from hamster DNA or a sample containing no DNA. The total number of cell-lines in the panel is 93.

  • Markers were considered polymorphic if heterozygotes and at least one class of homozygotes were detected in a sample of 30 individuals of Chinese descent. If only heterozygotes were detected, the marker was considered nonpolymorphic.

This Article

  1. Genome Res. 11: 1262-1268

Preprint Server