Table 2.
Number of Marker Pairs in LD
| Intermarker distance (cM) | n | P < 0.01 | P < 0.001 | ||||
| spouses | affecteds | combined | spouses | affecteds | combined | ||
| <1 cM | 11 | 11 | 11 | 11 | 10 | 11 | 11 |
| 1–2 cM | 18 | 9 | 13 | 14 | 7 | 10 | 12 |
| 2–3 cM | 14 | 2 | 8 | 11 | 1 | 4 | 7 |
| 3–4 cM | 18 | 4 | 6 | 7 | 1 | 2 | 4 |
| ≥4 cM | 842 | 17 | 16 | 12 | 0 | 3 | 4 |
| Total in 99.2 | 903 | 43 | 54 | 55 | 19 | 30 | 38 |
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P-values from a likelihood ratio test for LD. n, number of marker pairs. The spouse, affected, and combined samples consist of 386,837 and 1223 individuals, respectively.
