Genome-Wide Epistatic Interaction Analysis Reveals Complex Genetic Determinants of Circadian Behavior in Mice

Table 1.

The Summary of the Mean Phenotypic Values for Mice from all Generations of the Intercross

Trait Generation Mean (hr) SD (hr) Range N
Period C57BL/6J Female 23.60 0.05 23.52–23.67 12
C57BL/6J Male 23.64 0.08 23.52–23.80 11
BALB/cJ Female 23.02 0.73 21.82–23.65 6
BALB/cJ Male 22.80 0.53 22.08–23.50 11
F1 Female 23.50 0.10 23.28–23.65 12
F1 Male 23.42 0.15 23.23–23.70 12
F2 Female 23.43 0.40 22.45–24.68 98
F2 Male 23.56 0.33 22.75–24.62 98
Mean (hr) SD (hr) Range N
Phase C57BL/6J Female 0.25 0.40 −0.46–0.91 12
C57BL/6J Male 0.17 0.37 −0.57–0.57 11
BALB/cJ Female −3.14 1.13 −4.57–1.71 6
BALB/cJ Male −3.83 1.28 −6.63–−2.06 12
F1 Female −0.16 0.34 −0.80–0.46 12
F1 Male −0.45 0.53 −1.71–0.34 12
F2 Female −1.12 1.85 −10.00–1.93 98
F2 Male −1.51 2.20 −10.68–1.55 98
Mean (%) SD (%) Range N
Amplitude C57BL/6J Female 16.24 5.56 1.435–23.05 12
C57BL/6J Male 17.90 1.70 15.4–20.16 11
BALB/cJ Female 3.23 2.25 0.07–6.20 6
BALB/cJ Male 4.81 3.14 0.28–8.66 12
F1 Female 18.34 3.84 11.85–24.31 12
F1 Male 13.47 5.36 3.10–20.46 12
F2 Female 13.56 5.70 1.21–23.48 98
F2 Female 10.80 5.24 0.07–21.94 98
Mean (rev.) ×104 SD (rev.) ×104 Range ×104 N
Activity C57BL/6J Female 2.94 0.86 0.87–3.98 12
C57BL/6J Male 2.95 0.44 2.04–3.74 11
BALB/cJ Female 1.70 1.47 0.36–4.32 6
BALB/cJ Male 2.18 1.38 0.49–5.61 12
F1 Female 5.40 0.79 4.25–6.78 12
F1 Male 3.34 1.56 0.20–6.18 12
F2 Female 4.22 1.47 0.21–8.00 98
F2 Male 3.04 1.10 0.03–7.03 98
Mean SD Range N
Dissociation C57BL/6J Female 0.00 0.00 0–0 12
C57BL/6J Male 0.00 0.00 0–0 11
BALB/cJ Female 2.00 0.89 1–3 6
BALB/cJ Male 1.82 0.98 0–3 12
F1 Female 0.17 0.58 0–2 12
F1 Male 0.08 0.29 0–1 12
F2 Female 0.71 1.28 0–5 98
F2 Male 0.65 1.12 0–4 98

This Article

  1. Genome Res. 11: 959-980

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  1. January 2026, 36 (1)
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