Table 1.
Frequency of Confirmed SNPs in Coding Sequences
| Genes | Basepairs screened | Number SNP | Frequency of SNP | θ (×10−4) | ||||||
| total | non-syn | syn | total | non-syn | syn | total | non-syn | syn | ||
| ACAT2 | 1558 | 3 | 1 | 2 | 1/519 | 1/1558 | 1/779 | 3.41 | 1.136 | 2.274 |
| APOB | 40 | 0 | 0 | 0 | 0/40 | 0/40 | 0/40 | — | — | — |
| CH25H | 819 | 2 | 0 | 2 | 1/410 | 0/819 | 1/410 | 4.317 | — | 4.317 |
| CLA1 | 1650 | 3 | 2 | 1 | 1/550 | 1/825 | 1/1650 | 3.218 | 2.145 | 1.072 |
| HMGCR | 2667 | 1 | 1 | 0 | 1/2667 | 1/2667 | 0/2667 | 0.663 | 0.663 | — |
| LDLR | 2583 | 10 | 3 | 7 | 1/258 | 1/861 | 1/369 | 6.861 | 2.055 | 4.797 |
| NR1H2 | 1344 | 1 | 0 | 1 | 1/1344 | 0/1344 | 1/1344 | 1.317 | — | 1.317 |
| S1P | 3159 | 4 | 2 | 2 | 1/790 | 1/1580 | 1/1580 | 2.24 | 1.12 | 1.12 |
| SCAP | 3840 | 3 | 1 | 2 | 1/1280 | 1/3840 | 1/1920 | 1.382 | 0.46 | 0.921 |
| SREBF1 | 3575 | 1 | 1 | 0 | 1/3575 | 1/3575 | 0/3575 | 0.495 | 0.495 | — |
| SREBF2 | 3440 | 7 | 3 | 4 | 1/491 | 1/1147 | 1/860 | 3.605 | 1.543 | 2.058 |
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↵Includes one nonsense mutation.
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Average frequency of SNP.
