Figure 2.
Example of pericentromeric duplication using fuguization method. (A) A graphical view of the output for our method as displayed in the program PARASIGHT (J.A. Bailey, unpubl.). Compared to miropeats (B; Parsons 1995), all of the positions of similarity have been captured as continuous large alignments (C). An example of a large insertion-deletion in an alignment (D) demonstrates the ability of fuguization to traverse such regions returning larger more meaningful alignments. Lower thresholds (>500 aligned bases; >90% identity) were used for this test case compared to our genome analysis.
