Gene Structure Prediction and Alternative Splicing Analysis Using Genomically Aligned ESTs

Table 1.

Evaluation of Gene Boundary Identification

5′ Extension 3′ Extension Extension Split Correct Accuracy
Genscan 303 203 441 58 375 44%
TAP 89 66 147 40 662 78%
  • The predicted gene having the greatest overlap with the known genic region was taken as the reconstruction. 846 genomic templates served as the test set for both TAP andGenscan. (Extension) Number of predictions with ≥1 exon segment located outside of the known boundaries. (Split) Number of predictions that partition reference gene sequences into separate genic regions. (Correct) Number of predictions that are neither extended nor split.

This Article

  1. Genome Res. 11: 889-900

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