A Comparative Genomics Approach to Prediction of New Members of Regulons

(Downloading may take up to 30 seconds. If the slide opens in your browser, select File -> Save As to save it.)

Click on image to view larger version.

Figure 6.
Figure 6.

Training set TUs regulated by CRP and FNR and H. influenzaeTUs containing orthologs to genes in the training set. Genes in a TU are represented by rectangular boxes. Binding sites are represented by square boxes with gray box representing a weak site and black box representing a strong site. The distance between a binding site and the translation start is proportional to the real distance on the genomic sequence. Gene boxes and distances between genes are not in proportion. Orthology relationship is indicated by a solid line between the two genes involved. (+ and −) The strandness of a transcription unit. EC,E. coli; HI, H. influenzae; CRP, cAMP receptor protein; FNR, fumarate and nitrate reduction regulatory protein.

This Article

  1. Genome Res. 11: 566-584

Preprint Server