Table 1.
Characteristics of the Clones Selected and Their Deletions
| Clone no. | No.pts | % pts with cavitary disease | % of contacts with positive tuberculin | % of contacts with active disease | No.deleted bp | No. of DS | No. of deleted ORFs |
| 3160 | 41 | 5.4 | 28.6 | 9.7 | 17862 | 4 | 25 |
| 3743 | 5 | 0.0 | 0.0 | 0.0 | 31581 | 6 | 37 |
| M3061A | 2 | 0.0 | 40.0 | 0.0 | 26481 | 6 | 38 |
| 9700665 | 23 | 13.0 | 27.3 | 4.2 | 22547 | 5 | 27 |
| 9800608 | 24 | 12.5 | 34.1 | 2.4 | 14973 | 3 | 20 |
| 1254 | 20 | 15.0 | 27.1 | 1.6 | 23344 | 4 | 27 |
| 1209 | 5 | 20.0 | 25.0 | 4.6 | 16556 | 3 | 23 |
| 9802826 | 6 | 33.3 | 82.4 | 5.9 | 3758 | 2 | 4 |
| 1766 | 10 | 40.0 | 55.7 | 2.4 | 18916 | 3 | 23 |
| 2761 | 2 | 50.0 | 71.4 | 0.0 | 9236 | 1 | 14 |
| M4377A | 2 | 0.0 | 10.0 | 0.0 | 2308 | 1 | 3 |
| 1006 | 5 | 60.0 | 9.7 | 0.0 | 2890 | 1 | 3 |
| 9802501 | 3 | 66.7 | 93.8 | 5.9 | 15817 | 3 | 20 |
| 1122† | 1 | — | — | — | 9236 | 1 | 14 |
| 1843‡ | 1 | — | — | — | 0 | 0 | 0 |
| CDC1551§ | — | 80.3 | 4.9 | 9718 | 6 | 14 | |
| H37Ra″ | — | — | — | — | 0 | 0 | 0 |
| Average | 13248.4 | 2.9 | 17.2 | ||||
| 2 STD | 19276.0 | 4.1 | 24.3 |
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↵Isolates obtained from the previously reported outbreak: 3160 source case isolated in 1990, a second secondary case was diagnosed seven months later and another case in 1998. The following isolates were included because unusual characteristics: †, Rifampin-resistant with wild-type rpoB gene; ‡, Isoniazid-resistant with catalase-negative phenotype; §, Strain reported to have increased virulence12; ″, Attenuated variant of sequenced H37Rv strain.
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Pts, patients; bp, base pairs; DS, deleted sequence; ORF, open reading frame; STD, standard deviation.
