Figure 2.
Result from validation of the microarray-based genotyping system. Two mixtures of 25 synthetic oligonucleotide templates corresponding to one of the alleles at each SNP site were analyzed in minisequencing reactions on the microarrays to verify that both alleles of each SNP marker would be detected. (Left panel) The fluorescence image obtained from four detection reactions (A, C, G, T) with TAMRA-labeled ddNTPs. (Right panel) Order of the SNP markers on the array with the nucleotide variation at each site. The asterisk indicates those alleles that are detected from complementary DNA strands compared to earlier published literature.
