Table 1.
Variable Diallelic Loci Used in the Example Application
| Locus | Relative frequency | pv | Location | Reference |
| APOB | 2p24 | |||
| InDel | 0.683 | 0.000 | Exon 1 | Boerwinkle and Chan 1989 |
| XbaI RFLP | 0.525 | 0.002 | Exon 26 | Berg et al. 1986 |
| MspI RFLP | 0.899 | 0.009 | Exon 26 | Priestley et al. 1985 |
| EcoRI RFLP | 0.871 | 0.000 | Exon 29 | Shoulders et al. 1985 |
| PONl | 7q22 | |||
| L54M | 0.629 | 0.000 | Exon 3 | Humbert et al. 1993 |
| R192N | 0.718 | 0.010 | Exon 6 | Humbert et al. 1993 |
| LPL | 8p22 | |||
| PvuII RFLP | 0.526 | 0.000 | Intron 6 | Li et al. 1988 |
| HindIII RFLP | 0.721 | 0.012 | Intron 8 | Heizmann et al. 1987 |
| BstNI RFLP | 0.703 | 0.000 | Intron 9 | Funke et al. 1988 |
| APOAl-C3-A4 | 11q23 | |||
| InDel | 0.548 | 0.010 | 5′ of APOAl | Coleman et al. 1986 |
| PstI RFLP | 0.943 | 0.010 | 3′ of APOAl | Kessling et al. 1985 |
| SstI RFLP | 0.907 | 0.000 | Exon 4, APOC3 | Rees et al. 1983 |
| LDLR | 19p13 | |||
| TaqI RFLP | 0.911 | 0.017 | Intron 4 | Yamakawa et al. 1987 |
| StuI RFLP | 0.955 | 0.021 | Exon 8 | Kotze et al. 1986 |
| HincII RFLP | 0.556 | 0.000 | Exon 12 | Leitersdorf and Hobbs 1987 |
| AvaII RFLP | 0.552 | 0.000 | Exon 13 | Hobbs et al. 1987 |
| APOE | 19p13.2 | |||
| C112R | 0.833 | 0.000 | Exon 4 | Rall et al. 1982 |
| R158C | 0.922 | 0.000 | Exon 4 | Rall et al. 1982 |
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↵For the most common allele.
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Loci are shown with the proportion of lnTrig variability (pv) that they explain independently.
