Figure 2.
Eight-channel prototype of thermal cycling bath. Circulating water enters the sealed bath at the bottom, flows around the pipette tips, and exits at the top. One of the tips is shown loaded with a sacrificial water slug (not easily visible in the figure) followed by four 500 nL slugs of loading dye for purposes of this illustration. The tips are heat sealed at the bottom end and sealed with a plunger at the top end. After cycling, the heat-sealed end is cut to remove the sample.
