Alternatively spliced gene products of NICE-3. The nucleotide sequences of the three cDNA clones were identical except for the lacking exons (broken lines) of clones 3038m19 (exon 279–380) and 1023j12 (exons 279–380 and 499–552). Incomplete 5′-termini of clones 3038m19 and 3038j13 were filled up with overlapping sequences of clone 1023j12 (a) and EST T27537 (b). Sequence information derived from the respective clones is represented by open boxes; ORFs are shaded gray. The first nucleotide of the putative initiation methionine codon, exon boundaries, and the last nucleotide of the coding sequence, as well as the size of the predicted protein are indicated for each transcript. Additional spliced exons and combinations of them were identified in ESTs by similarity search: exon 202–278 in AA354455 from Jurkat T-cells, exons 202–278 and 279–380 in AA463392 from total fetus, exon 381–498 in AA057488 from colon, exons 279–380 and 381–498 in Z42265 from infant brain.
