Identification of Human Epidermal Differentiation Complex (EDC)-Encoded Genes by Subtractive Hybridization of Entire YACs to a Gridded Keratinocyte cDNA Library

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Figure 1.
Figure 1.

Hybridization of YACs 986_e_10 and 950_e_2#9 to a high-density filter of the gridded keratinocyte cDNA library. Autoradiographs show a quarter of a blot containing 18,432 double-spotted cDNA clones, which was successively hybridized with 32P-labeled DNA derived from YACs 986_e_10 and 950_e_2#9, respectively. Positive clones are detected by two spots arranged in a specific pattern. Clones identified with both YACs were subtracted. Arrows indicate examples of a subtracted clone (black arrows) and of potentially EDC-specific cDNAs (white arrows).

This Article

  1. Genome Res. 11: 341-355

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