Establishment of a Chemical Synthetic Lethality Screen in Cultured Human Cells

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Figure 1.
Figure 1.

De novo and salvage pathways of purine biosynthesis. Key enzymes are underlined. Arrows indicate the action of enzymes. The sites of inhibition by mycophenolic acid (MPA), ribavirin (RI), mizoribine (MI), and aminopterin (AM) are marked.

This Article

  1. Genome Res. 11: 266-273

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