Low-Complexity Regions in Plasmodium falciparum Proteins

Table 1.

Comparative Analysis of Hydrophilic Low-Complexity Segments in Different Lower Eukaryotes

P. falciparum chr. 2 P. falciparum chr. 3 P. berghei S. cerevisiae chr. II D. discoideum
Total proteins 205 215 34 428 491
Proteins containing I-c segments 88.2% 94.0% n.d. 52.8% n.d.
Complex segments 598 (47109 aa) 690 (55558 aa) 59 (10843 aa) 685 (137082 aa) 1056 (180577 aa)
I-c segments identified by SEG 415 (98662 aa) 491 (121017 aa) 35 (6404 aa) 379 (43454 aa) 624 (89259 aa)
Hydrophilic I-c segments 357 (92371 aa) 449 (116367 aa) 32 (6150 aa) 300 (36128 aa) 541 (80519 aa)
A+T content in coding regions 75.7% 76.8% 68.9% 60.4% 67.6%
h I-c compl h I-c compl h I-c compl h I-c compl h I-c compl
Percentual amino acid A 1.45 2.90 1.22 3.39 3.79 5.05 5.70 5.53 3.28 5.21
Composition in hydrophilic C 1.35 2.60 1.53 2.55 0.70 2.80 0.40 1.54 0.96 1.85
Low complexity (h I-c) and in D 6.77 5.74 7.35 5.57 6.28 5.76 6.37 5.74 4.81 5.66
Complex (compl) segments E 8.07 6.56 7.14 6.26 9.80 6.90 7.53 6.07 6.74 6.07
F 3.70 5.14 3.84 5.73 2.62 4.37 2.51 4.83 2.37 4.84
G 2.61 4.28 2.21 4.17 3.38 5.73 3.89 5.40 4.60 5.90
H 2.40 2.61 2.52 2.74 1.23 1.86 2.00 2.30 1.71 2.22
K 13.29 9.70 12.90 9.70 12.49 8.55 7.86 7.28 7.30 7.37
I 9.07 8.40 9.32 9.61 9.90 8.25 4.96 6.89 6.49 7.55
L 6.90 8.41 6.88 9.30 7.33 8.83 7.99 9.51 7.03 8.68
M 2.06 2.67 2.11 2.70 1.19 2.09 1.50 2.20 0.91 2.22
N 16.38 8.53 18.13 8.59 11.66 6.94 8.19 5.69 12.97 5.79
P 1.57 2.96 1.56 3.00 3.06 3.64 5.08 4.30 5.18 4.18
Q 2.65 3.12 2.54 3.14 3.40 2.74 5.57 3.71 7.98 4.09
R 2.25 3.31 2.36 3.47 1.98 3.54 4.19 4.60 2.62 4.03
S 6.27 6.67 6.18 6.57 8.03 9.79 12.96 8.00 12.04 7.48
T 4.02 4.96 3.65 4.80 5.19 5.19 6.91 5.62 6.97 5.71
Y 5.44 5.61 6.27 6.21 4.28 4.41 2.06 3.74 2.22 3.76
V 3.53 5.04 3.28 5.12 3.45 5.85 4.10 5.86 3.54 6.21
W 0.19 0.95 0.22 0.96 0.26 0.93 0.28 0.28 0.27 1.12

This Article

  1. Genome Res. 11: 218-229

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