Two Functional Copies of the DGCR6 Gene Are Present on Human Chromosome 22q11 Due to a Duplication of an Ancestral Locus

(Downloading may take up to 30 seconds. If the slide opens in your browser, select File -> Save As to save it.)

Click on image to view larger version.

Figure 2.
Figure 2.

cDNA sequence of the DGCR6 and DGCR6L genes. The sequence represents the cDNA sequence of DGCR6. Nucleotide changes present in DGCR6L are indicated above the sequence, and corresponding amino acid changes in gray boxes below the amino acid. The original sequence (Demczuk et al. 1996; GenBank accession no.X96484) differs from the sequence shown here by a single base insertion of G (arrow) at position 221 of the originally published sequence, shown here between nucleotide position 302 and 303. The putative initiator methionine at nucleotide position 97 is indicated by the shaded box. The putative initiator methione of the original sequence is indicated by the open box at position 504.

This Article

  1. Genome Res. 11: 208-217

Preprint Server