Comparative Sequence Analysis of the Imprinted Dlk1–Gtl2 Locus in Three Mammalian Species Reveals Highly Conserved Genomic Elements and Refines Comparison with the Igf2–H19 Region

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Figure 3.
Figure 3.

Identification of highly conserved elements. (A) The strategy for the identification of conserved elements is described by the scheme above the table. The table shows the numbers of conserved elements identified on different levels of sequence conservation. The inclusion of the human–sheep, and mouse–sheep alignments results in a reduction in numbers of identified elements. This reduction is described by the proportions of identified elements related to the values given for the human–mouse alignment only. (B) Positions of the 20 highly conserved elements (>100 bp, >70% identity) in the mouse sequence (GenBank accession no. AJ320506) that were identified in all three alignments. Additionally, the lengths, G+C content, and special features of the individual elements are shown.

This Article

  1. Genome Res. 11: 2085-2094

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