Figure 4.
Validation approaches. (A) Evaluating the effectiveness ofDIAN by comparing assignments made to a reference ontology. Selected nodes from Gene Ontology (GO) ontologies were manually associated with nodes in the DIAN ontologies. Sequences assigned to these GO nodes by the MGI were processed by theDIAN pipeline to compare the assignments made byDIAN with those made by MGI. (B) Associating nodes and sequences from a reference ontology to a DIAN ontology for comparative evaluation. To estimate the error rates associated with theDIAN assignment algorithms, we compared mouse sequences mapped via DIAN (A) with assignments made to GO ontologies by MGI.
