
Identity distributions between finished sequences and BESs for RPCI-23, RPCI-24, and RPCI-11. The sequence comparison between mBESs and mouse contig sequences were done as described in Fig. 5. The average identity was 99.2% with a SD of 0.6% for RPCI-23 (●), and 99.4% with an SD of 0.5% for RPCI-24 (○). The same analyses were performed by comparing a total of 62,226 human BES pairs (3.4× coverage) from RPCI-11 library with finished human chromosome 21 sequence (34 Mb). A total of 779 pairs (3.4× coverage) were identified matching the chromosome. The average identity was 99.4% with a SD of 0.6% (▴).











