Whole Genome Comparison of Campylobacter jejuni Human Isolates Using a Low-Cost Microarray Reveals Extensive Genetic Diversity

Table 4.

Divergence in the 20.4 kb NCTC 11168 Lipo-oligosaccharide Biosynthetic Locus in the Campylobacter jejuni Strains Studied

Gene name Function Clone content (%) Phase variable 81116 81-176 X G1 P1 P2 P3 P4 PHLS 01 PHLS 02 PHLS 03
Cj1131 galE Cj1131 (73) + + + + + + + + + + +
Cj1132 unknown Cj1132(80) + + + + + + + + + + +
Cj1133 (11)
Cj1133 waaC Cj1132(20) (+) + (+) (+) + (+) + + + +
Cj1133(100)
Cj1134(19)
Cj1134 htrB Cj1134(67) + + + + + + + + + + +
Cj1135(4)
Cj1135 glycosyltransferase Cj1135(53) + + + + + + + + +
Cj1136 glycosyltransferase Cj1136(89) (+) + + + + + + +
Cj1137(3)
Cj1137 unknown Cj1136(13) (+) + + (+) (+) + (+) +
Cj1137(100)
Cj1138(18)
Cj1138 galactosyltransferase Cj1138(67) + + (+) + (+) + + +
Cj1139 wlaN Cj1138(30) + + + + + + +
Cj1139(96)
Cj1140 cst Cj1140(93) + + + + (+) + + +
Cj1141(47)
Cj1141 neuBl Cj1140(26) + + + (+) + + + +
Cj1141(100)
Cj1142(6)
Cj1142 neuCl Cj1141(29) (+) + + + + + + +
Cj1142(98)
Cj1143 neuAl Cj1143(42) + + + + + + +
Cj1144 unknown Cj1143(15) + + + + + + +
Cj1144(75)
Cj1145 unknown Cj1143(3) (+) + + + + (+) + +
Cj1144(100)
Cj1145(100)
Cj1146(76)
Cj1146 waaV Cj1146(89) + + + + + + (+) (+) + (+) +
Cj1148(9)
Cj1148 waaF Cj1148(80) + + + + + + + + + + +
Cj1149(2)
Cj1149 gmhA Cj1149(92) + + + + + + + + + + +
Cj1150(27)
Cj1150 rfaE Cj1149(23) + + + + + + (+) (+) + + (+)
Cj1150(94)
Cj1151 rfaD Cj1150(35) + + + + + + + + + + +
Cj1151(83)
Cj1152 phosphatase Cj1152(76) + + + + + + + + + + +
Cj1153(100)
  • A + or − indicates that the red/green hypridization signal intensity ratio is >0.5 or <0.5, respectively.

  • (+) indicates the possibility that the gene may be absent or highly divergent even though the red/green hybridization signal intensity ratio is >0.5 (see Methods).

  • Putative gene function based on annotation (Parkhill et al. 2000).

  • Genes contain intragenic homopolymeric tracts indicating potential phase variable expression (Parkhill et al. 2000).

  • Linton et al. 2000b.

  • Linton et al. 2000a.

  • NB: Cj1447 was originally designated a CDS, but was unannotated in the final genome annotation (Parkhill et al. 2000).

This Article

  1. Genome Res. 11: 1706-1715

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