Evolutionarily Conserved Sequences on Human Chromosome 21

Table 1.

Comparison of the Array Data with BLASTAlignments for Twenty-Two Human Chromosome 21 Genes with Previously-Sequenced Mouse Orthologs

BLAST Expect score No. of BLAST matches Percent identified by array Total bp (%) overlap BLAST % ID Array % CON
10−10–10−05 20 50 658 (42) 88 71
10−20–10−10 47 55 2359 (41) 89 72
10−30–10−20 40 72 3472 (45) 89 72
10−40–10−30 24 79 2799 (51) 89 68
10−60–10−40 29 90 4390 (54) 90 69
<10−60 30 100 9652 (49) 90 65
Total 190 74 23330 (49) 89 69
  • Column 1, BLAST matches of 190 exons divided into six classes based on their Expect scores. Column 2, the number of electronic matches in the class. Column 3, the percent of electronic matches in the class that were identified as conserved elements by the array analysis. For the conserved elements identified by bothBLAST and the array, Column 4 lists the total number of basepairs in the electronic matches and the percent of those basepairs identified by the array. Column 5, the mean percent identity of the electronic matches in class. Column 6, the mean percent conformance of the base pairs identified by both BLAST and the array.

This Article

  1. Genome Res. 11: 1651-1659

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