Table 2.
Most Versatile Single-Domain Superfamilies
| No.func | No.prot | Sfam comb | Function | SWISS-PROT ID | SWISS-PROT function |
| E1.11.1 | GSHP_RAT | Plasma Glutathione Peroxidase (1.11.1.9) | |||
| 263# | DYL5_CHLRE | Dynein, Flagellar Outer Arm–C. reinhardtii | |||
| D260# | BSAA_BACSU | Glutathione Peroxidase Homolog Bsaa | |||
| 268# | REHY_TORRU | Rehydrin–Tortula ruralis (Moss) | |||
| 11 | 69 | 3.38.1 | 266# | PHOS_HUMAN | Phosducin (33 Kd Phototransducing Protein) |
| 269# | REHY_ORYSA | Rad24 Protein–Oryza sativa (Rice) | |||
| 272# | THIO_BPT4 | Thioredoxin (Bacteriophage T4) | |||
| D271#272# | TDX2_BRUMA | Thioredoxin Peroxidase 2 | |||
| 261# | BTUE_ECOLI | Vitamin B12 Transport Periplasmic Protein Btue | |||
| 342# | BRAZ_PENBA | Brazzein–Pentadiplandra brazzeana | |||
| 376#336# | SCKK_TITSE | Neurotoxin Ts-Kapa (Tsk)–(Brazilian scorpion) | |||
| 341#356# | AF2B_SINAL | Cysteine-Rich Antifungal Protein 2b (Afp2b) | |||
| 10 | 28 | 7.3.6 | 343# | DEFA_ZOPAT | Defensin, Isoforms B And C–Zophobas atratus |
| 361# | DMYC_DROME | Drosomycin Precursor (Cysteine-Rich Peptide) | |||
| 361#376# | SCX5_BUTEU | Insectotoxin I5a–(Lesser Asian scorpion) | |||
| 336# | SCX3_LEIQH | Leiuropeptide Iii–(Scorpion) | |||
| 203# | SIA1_SORBI | Small-Pr Inhibitor Of Insect Alpha-Amylases | |||
| 310# | AB18_PEA | Aba-Responsive Protein Abr18–Garden Pea | |||
| 311# | DRR3_PEA | Disease Resistance Response Protein Pi49 | |||
| 7 | 34 | 4.79.3 | 231# | MPAA_CORAV | Major Pollen Allergen Cor A 1,–Eu. Hazel |
| 312# | L18B_LUPLU | Protein L1r18b (LIpr10.1b) | |||
| E3.1.– | RNS2_PANGI | Ribonuclease 2 (3.1.–/–)–Panax Ginseng | |||
| 314# | SAM2_SOYBN | Stress-Induced Protein Sam22 | |||
| 184# | CSF2_SHEEP | Colony-Stimulating Factor | |||
| 381#564#184# | IL4_RAT | Interleukin-4 (B-Cell Igg Diff. Factor) | |||
| 7 | 43 | 1.26.1 | 185# | LIF_HUMAN | Leukemia Inhibitory Factor (Lif) |
| 187# | PRL_ANGAN | Prolactin Precursor (Prl)– | |||
| 186# | PLF3_MOUSE | Proliferin 3 Mitogen-Regulated | |||
| 188# | SOMA_PAROL | Somatotropin (Growth Hormone) |
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The most versatile superfamilies in single-domain proteins as determined from their functional description in SWISS-PROT, with some representatives. The keyword combinations in the fourth column were based either on the first three components of their EC numbers (for enzymes) or derived automatically by comparing the DE description line of SWISS-PROT entries to a list of synonymous keywords athttp://bioinfo.mbb.yale.edu/partslist/func. A keyword number starting with a D indicates an enzyme that does not have an assigned EC number in its description in SWISS-PROT.
