Figure 4.
Localization of LCR15–1, LCR15–2, and LCR15–3 on 15q by FISH analysis. Probes used were RZPD-1070i12 (15q26.1) (A) and RZPD-161c1 (15q24) (B). RZPD-1070i12 clone hybridizes to two regions on 15q, the signal on 15q24 being weaker than on 15q26.1. RZPD-161c1 clone hybridizes on 15q24 and on 15q26.1, but also on 15q11-q13 (weaker signal). (C) Interphase nuclei analysis with probe RZPD-161c1 and control probe HGMP-216i14 (15q25.3; see Fig. 1A). The hybridization conditions for all three experiments were identical. At lower stringency conditions other FISH signals on chromosomes 2 and Y could be seen (not shown).
