Table 1.
Summary of Female Sterile Mutants
| Genes required for patterning in the germarium | |||
| Locus | Map position¶ | Alleles | Notes |
| brainiac (brn) | 4B2 | brn198 | Both alleles are hemizygous lethal, paternally rescued maternal |
| brn228 | effect lethal over brnfs107. brn228/brn228 is a temperature sensitive lethal. | ||
| fs(1)Yb | 3B1 | fs(Yb)72 | See text |
| ovarian tumor (otu) | 7E9 | otu55 otu67 otu139 | otu55 and otu99 produce ovarian tumors (ONC class; Lindsley and Zimm 1992), out67 produces later phenotypes typical of the DIF class. |
| sans filles (snf) | 4F2 | snf148 | Tumorous germarium |
| sex lethal (Sxl) | 6F5 | Sxlf79 | Female lethal in hemizygotes. Homozygotes have tumorous ovaries. |
| fs(1)100 | lethal | Associated with semi-lethality. 5% supernumary nurse cells (5 ring canals on oocyte). | |
| fs(1)124 | 9D1–2 | See text | |
| fs(1)217 | 26cM ± 2.5 | See text | |
| fs(1)259 | 14B1-16A7 | See text | |
| Genes required in mid-oogenesis | |||
| Locus | Map position¶ | Alleles | Notes |
| dunce (dnc) | 3D2 | dnc221b | See text |
| dnc225 | |||
| fs(1)K10 | 2F1 | fs(1)K1047 | |
| fs(1)K10130 | |||
| singed | 7D2 | sn77sn184 | |
| fs(1)3 | 5C5-5D1? | Weak phenotype over deficiency, see text• | |
| fs(1)140 | 43cM ± 2.5 | See text | |
| fs(1)186 | 14C-15A6 | ||
| fs(1)234 | 5A8-5C2 | See text | |
| Mutations resulting in cell death or degeneration | |||
| Locus | Map position¶ | Alleles | Notes |
| fs(1)56 | lethal | Variable germ-line degeneration after stage 9. Few eggs, some short or fused dorsal appendages. | |
| fs(1)60 | 0-2cM ± 1.4 | Variable germ-line degeneration after stage 10. No eggs laid. | |
| fs(1)127 | 1cM ± 1 | Degeneration in stage 9 or 10, sometimes earlier (stage 6). Oocyte growth retarded after stage 9, nurse cell nuclei also small.Some tumorous cysts | |
| fs(1)137a | lethal | Associated with semi-lethality. Degeneration of germ-line cells usually at stage 9 but at variable stages starting in the germarium. | |
| fs(1)162 | 9cM ± 2.7 | Variable degeneration after stage 9, majority normal to stage 14. No eggs laid. | |
| fs(1)164 | 30cM ± 3.4 | See text | |
| fs(1)192 | 24cM ± 1.6 | Variable degeneration after stage 10. Rare cases of 8− or (approx.) 32− cell cysts. Most appear normal to stage 14. Females lay rare collapsed egg remnants. | |
| fs(1)221a | 15-16cM ± 2.4 | See text | |
| fs(1)242 | lethal | Variable degeneration after stage 9. Females lay eggs with fused or reduced dorsal appendages. | |
| fs(1)250 | 21cM ± 1 | Degenerate after stage 12. Females lay small number of collapsed egg remnants. | |
| fs(1)260 | Degeneration in stage 10 or later. Rare failed or retarded border cell migration. Rare supernumerary nurse cells (<5%). | ||
| fs(1)261EL | lethal | Degeneration after stage 8. Associated with semi-lethality. | |
| Genes reguired for egg shell formation | |||
| Locus | Map position¶ | Alleles | Notes |
| dec-1 | 7C6 | dec-1H12 | All alleles result in few or no eggs laid |
| dec-1H13 | |||
| dec-1H15 | |||
| fs(1)38 | 25cM ± 2.3 | fs(1)38 | Few eggs, defective chorion |
| fs(1)161 | |||
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¶ Cytological map intervals denote limits of deficiencies that uncover the mutation; “lethal” indicates the presence of a lethal mutation on the chromosome (in the fslocus or outside of it) that prevents recombination mapping.
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↵Mapping revealed a contamination problem.
