Genomewide Function Conservation and Phylogeny in the Herpesviridae

Table 1.

Herpesvirus Genomes Used to Construct Homologous Protein Families

Subfamily and sublineage Virus name (strain) Acronyms GenBank Accession no. ORFs Length (Kb)
Alphaherpesviruses
α1 Human herpesvirus 1 (17) HSV-1/HHV-1 X14112 77 152
α1 Human herpesvirus 2 (HG52) HSV-2/HHV-2 Z86099 77 154
α2 Human herpesvirus 3 VZV/HHV-3 X04370 71 124
α2 Equine herpesvirus 1 (Ab4p) EHV-1 M86664 80 150
α2 Equine herpesvirus 4 (NS80567) EHV-4 AF030027 79 145
α2 Bovine herpesvirus 1 (K22) BHV-1 AJ004801 73 135
α3 Gallid herpesvirus 2 (HPR524) GHV-2 AB024414 65 110
Betaherpesviruses
β1 Human herpesvirus 5 (AD169) HHV-5/HCMV X17403 203 229
β2 Human herpesvirus 6 A (U1102) HHV-6 (A) X83413 121 159
β2 Human herpesvirus 6 B (HST) HHV-6 (B/HST) AB021506 115 161
β2 Human herpesvirus 7 (JI) HHV-7 (JI) U43400 107 144
Gammaherpesviruses
γ1 Human herpesvirus 4 (B95-8) HHV-4/EBV V01555 86 172
γ2 Alcelaphine herpesvirus 1 (C500) AHV-1 AF005370 70 130
γ2 Ateline herpesvirus 3 (73) HVA-3 AF083424 71 108
γ2 Macaca mulatta rhadinovirus (17577) RRV AF083501 80 133
γ2 Saimiriine herpesvirus 2 HVS X64346 76 112
γ2 Equine herpesvirus 2 (86/87) EHV-2 U20824 79 184
γ2 Human herpesvirus 8 HHV-8/KSHV U75698 82 137
γ2 Murine herpesvirus 68 (WUMS) MHV-68 U97553 80 119
  • Number of open reading frames as extracted from GenBank entry (Benson et al. 1999).

  • HSV-1; herpes simplex virus-1

  • HSV-2; herpes simplex virus-2

  • VZV; Varicella Zoster virus

  • HCMV; human cytomegalovirus

  • EBV; Epstein-Barr Virus

  • HVA-3; herpesvirus ateles-3

  • RRV; rhesus rhadinovirus

  • HVS; herpesvirus saimiri

  • KSHV; Kaposi's sarcoma associated herpesvirus

This Article

  1. Genome Res. 11: 43-54

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