Gene Expression Changes Triggered by Exposure of Haemophilus influenzae to Novobiocin or Ciprofloxacin: Combined Transcription and Translation Analysis

Table 2.

Genes with Changed Expression Levels after Addition of 12 ng/mL of Novobilocin

No. Gene product Fold change mRNA(protein)
10 min 30 min 60 min
hi0567 DNA gyrase, subunit B 2.0 2.2 1.8
hi0808 Ribosome releasing factor −2.4 (NC) −2.1 (NC) −2.0 (−3.1)
hi1365 Topoisomerase I −1.9 −2.2 −1.8
hi1048 Hypothetical protein −2.6 −3.2 −1.8
hi1507 Hypothetical protein NC (−3.7) NC (−2.6) NC (−2.0)

  • ↵Numbering according to Fleischmann et al. (1995).

  • ↵Standard deviations were below 20%.

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  1. Genome Res. 11: 28-42

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