Biased Distribution of Inverted and Direct Alus in the Human Genome: Implications for Insertion, Exclusion, and Genome Stability

Table 3.

Influence of Orientation and Separation Distance on AluPairs Containing a Young Subfamily Member

Orientation		Separation distance (b + c) (bp)		Sample size		YoungAlus
Orientation		Separation distance (b + c) (bp)		Sample size		no.	%
Inverted
CD	0–40	815	175	21.5
	41–80	1049	187	17.8
	>80	8082	1319	16.3
DC	0–40	765	173	22.6
	41–80	945	174	18.4
	>80	7907	1396	17.6
Direct
CC	0–40	7031	1580	22.5
	41–80	2133	353	16.5
	>80	10890	1810	16.6
DD	0–40	6689	1493	22.3
	41–80	2071	318	15.3
	>80	11707	1977	16.8

↵b + c (in bp)
↵ Alu subfamilies Alu-Y,Alu-Ya1, Alu-Yb8, Alu-Ya5 andAlu-Ya8

This Article

Genome Res. 2001. 11: 12-27

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