Comparative Maps of Human 19p13.3 and Mouse Chromosome 10 Allow Identification of Sequences at Evolutionary Breakpoints

Table 2.

Pulsed-Field Gel Electrophoresis (PFGE) Data for Markers on Mouse Chromosome 10 in the 19p13.3 Homology Region

Probes Genbank Nru Not Mlu Cla Swa Sal Pme SgrA Sfu Source
*K17 – ≪70 ≪70 450 <60 320 190,250 210 110,90 190 D. Jenne unpubl.
Shc2 T05885 ≪70 ≪70 450 <60 320 190,250 210 110,90 190 ATCC #82569
Bsg D82019 70,90 60 450 220,190 270 190,250 190 270 190 T. Miyauchi
Lmet1 L76741 70,90 60 450 220,190 270 190,250 190 270 190 D. Jenne
*K16 – 70,90 60 <60 220,190 270 190,250 190 270 190 D. Jenne unpubl.
*K14 – 100 150 250 280 310,180,150 140,80 440 320 450,270,150 D. Jenne unpubl.
Ptb X52101 100 150 250 ND 310,180,150 140,80 440 320 450,270,150 K. Brady
Ela2 X04576 100 150 250 ≪70 100 300 440 320 450,270,150 D. Jenne
Adn X04673 100 150 250 ≪70 100 300 440 320 450,270,150 D. Jenne
*K79 – 90 90 250 80 90 ND 440 320 450,270,150 D. Jenne
Gpx4 AJ012104 90 70 250 250 220 280 440 180 450,270,150 F. Chu
Cirbp D78135 150 200 250 250 280 ldr 440-440+ 420,350,280 210 280 IMAGE #329445
Efna2 U14941 150 200 250 250 280 ldr 400-440+ 420,350,280 210 280 W. Chung
Pcsk4 D01093 ≪90 80 ≪90 550,330 280 ldr 440-100 420,350,280 210 280 M. Mbikay
Tcfe2a D16631 300 150 50,100 350 110 ldr 440-100 420,350,120 70 190,140 T. Kadesch
D10Bwg1364e N28107 300 100 60 440,380,340,280 90 180 440,350 340 140 K. Brady
Ap3d AB004305 300 70 250 ND ND ND ND 340 ND IMAGE #519977
Amh/Sap62 X83733 <50 440 250 440,380,200,150 430 340 570,440 90 280,90 R. Behringer
Oaz1 U84291 100 440 80,100 440,200,150 420 340 90,440 200 110,390 L. Ghoda
Lmnb2 X54098 100 440 80,100 440,200,150 420 340 90,440 200 110,390 G. Krohne
Gng7 U38499 240 440 90 80,100,570 420 70,160,200 450 90,200 270,360 G. Sutcliffe
Thop1 M61142 240 440 120,250? 570 220 <70 450 100 270,360 C. Abraham
D10Bur1e AA530431 240 440 250 570 220 <70 450 100 270,360 IMAGE#931394
D10Wad2 – <50 440 150,220 ND 220 ND ND ND ND R.Baldocchi
Map2k2 S68267 <100 440 150,220 300,560,570 220 <80 450 100 270,360 B.Brott
Minta – 190 440 150,220 300,560,570 220 80 450 200,250 70 M.Taketo
Dapk3 AA023742 190 <50 150,220 300,560,570 220 160 450 200,250 130 IMAGE# 457325
D10Sut1e D21389 190 90 200 300,560,570 70 160 520 <90 130 IMAGE# 329416
Matk D45243 190 90 200 300,560,570 70 160 520 <90 130 R. White
Tbxa2r D10849 80 90 200 300,560,570 120 320 520 90,270 <70 T. Namba
Hmg20b AA106132 80 90 200 300,560,570 120 320 520 90,270 <70 IMAGE #522081
Gna11 M57617 210 100 260 120 200 320 520 70,170 180 T. Wilkie
Gna15 M80632 210 100 260 120 200 320 520 70,170 180 T. Wilkie
Grg L12140 210 1000 260 120 200 70 520 100,170 180 PCR product
Sirt6 AA839912 210 ND 260 ≪90 200 ND 520 ND 180 IMAGE #1259892
D10Bur2e W61992 210 ND 260 240 200 470-500 520 100,170 180 IMAGE #374959
Nfyb X55316 210 1000 900,1200 250 80,100 600 550,360,340 450 370,280,260 D. Mathis

  • Fragment sizes detected by gene probes are shown in kilobases for several relevant enzymes, as determined by PFGE mapping. Markers/genes are shown in order from centromere to telomere. More than one gene on a line indicates that PFGE mapping could not resolve the order. Accession numbers are Genbank. All are mouse DNA sequences except forThop1, where only rat sequence is available and given.

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  1. Genome Res. 10: 1369-1380

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