Table 2.
Human Genes with Two or More Zebrafish Orthologs
| Human gene | Reference (NCVI unigene) | Human map position | Zebrafish ortholog | Reference (NCBI gi) | Zebrafish map position |
| HES5 | no ref | 1.49-52cM | her2 | 1279391 | 8.472cR |
| her4 | 1279395 | 23.99cR | |||
| HFH2 | Hs.166188 | 1.95-102cM | fkd8 | 2982352 | 8.299cR |
| fkd6 | 2982348 | 6.273cR | |||
| SOX11 | Hs.32964 | 2.0-32cM | sox11a | NA | 17.234cR |
| sox11b | NA | 20.499cR | |||
| RARA | Hs.173205 | 2.51-54cM | rara2a | 704369 | 12.125cR |
| rara2b | 215025 | 3.161cR | |||
| SIX3 | Hs.227277 | 2.73-88cM | six6 | 3047418 | 12.188cR |
| six3 | 304716 | 13.278cR | |||
| EN1 | II.2019 | 2.127-134cM | eng4 | 4322043 | 1.59cR |
| eng1 | 62515 | 9.9cR | |||
| DLX2 | Hs.419 | 2.182-188cM | dlx5 | 1620515 | 1.179cR |
| dlx2 | 460126 | 9.131cR | |||
| IHH | Hs.69351 | 2.200-215cM | ehh | 1616584 | 6.115cR |
| hha | NA | 9.140cR | |||
| FZD5 | Hs.152251 | 2.211-218 | fz8a | 4164470 | 24.133cR |
| frz-zg06 | 1245193 | 2.438cR | |||
| FZD7 | Hs.173859 | 2.200-206cM | frz-zg07 | 1245195 | 9.170cR |
| fb38g02 | 6.115cR | ||||
| frz-zg13 | 1245207 | 6.129cR | |||
| GATA2 | Hs.760 | 3.142-146cM | gata1 | 1132418 | 11.230cR |
| gata2 | 1132420 | 11.390cR | |||
| ATP1B3 | Hs.76941 | 3.157-158cM | atp1b | 974773 | 2.150cR |
| fb13c07 | 15.57cR | ||||
| EPHA5 | Hs.31092 | 4.68-78cM | fb82e05 | 24.301cR | |
| rtk7 | 3005904 | 24.301cR | |||
| NPY1R | Hs.169266 | 4.157-169cM | zya | 3098345 | 17.79cR |
| zyb | 2739140 | 8.563cR | |||
| zyc | 3098347 | 10.385cR | |||
| EFNA5 | Hs.37142 | 5.108-116cM | al1 | 1834430 | 8.10cR |
| ephra5 | 2462952 | 21.129cR | |||
| CSX | Hs.54473 | 5.161-163cM | nkx2.7 | 1518150 | 8.505cR |
| nkx2.5 | 1518148 | 14.341cR | |||
| MSX2 | Hs.89404 | 5.185-196cM | msxe | 1399516 | 14.27cR |
| msxa | 608508 | 14.464cR | |||
| msxd | 62544 | 21.211cR | |||
| ISL1 | Hs.505 | 5.54-61cM | islet1 | 497897 | 5.143cR |
| islet2 | 1037165 | 25.406cR | |||
| islet3 | 1037167 | 25.406cR | |||
| AHR | Hs.170087 | 7.24-35cM | ahr2 | 4321818 | 22.88cR |
| ahr | 2764987 | 16.196cR | |||
| EVX1 | Hs.99967 | 7.38-42cM | eve1 | 475049 | 3.113cR |
| evx1 | no ref. | 16.175cR | |||
| HOXA | N/A | 7.39-40cM | hoxa13b | 4322052 | 16.175cR |
| hoxa4a | 4322059 | 19.170cR | |||
| EN2 | Hs.134989 | 7.167-175cM | eng2 | 62517 | 7.158cR |
| eng3 | 62521 | 2.343cR | |||
| SHH | Hs.121539 | 7.181-184cM | shh | 5714439 | 7.158cR |
| twhh | 1171139 | 2.346cR | |||
| SLUG | Hs.93005 | 8.57-68cM | sna2 | 841423 | 23.41cR |
| sna1 | 468620 | 11.284cR | |||
| NOTCH1 | II.4851 | 9.136-148cM | notch1b | 2569967 | 5.267cR |
| notch1 | 433866 | 21.75cR | |||
| RXRA | Hs.20084 | 9.143-166cM | rxrg | 1046288 | 5.222cR |
| rxra | 1046294 | 2.309cR | |||
| FTH1 | Hs.62954 | 11.16-23cM | fb06g09 | 7.45cR | |
| fb01e08 | 24.144cR | ||||
| WNT11 | Hs.108219 | 11.80-84cM | wnt11 | 3169686 | 5.125cR |
| wnt11r | NA | 10.306cR | |||
| HSPA10 | Hs.180414 | 11.128-132cM | hsc70.1 | 1408566 | 3.113cR |
| fb01g06 | 10.304cR | ||||
| SPON1 | Hs.5378 | 11.24-25cM | fspdin2 | 2529226 | 25.70cR |
| mindin1 | 2529220 | 14.379cR | |||
| mindin2 | 2529222 | 14.341cR | |||
| HOXC | N/A | 12.70-72cM | hoxc5a | 414104 | 23.324cR |
| hoxc13b | 4322091 | 11.459cR | |||
| ASCL1 | Hs.1619 | 12.106-113cM | zasha | 540237 | 4.149cR |
| zashb | 540239 | 7.177cR | |||
| OTX2 | II.5015 | 14.0-1cM | otx2 | 540243 | 17.304cR |
| otx3 | 633134 | 1.381cR | |||
| RTN1 | Hs.99947 | 14.54-58cM | deltab | 2772824 | 5.125cR |
| dla | 2809388 | 1.395cR | |||
| HOXB | N/A | 17.62-69cM | hoxb4a | 341108 | 3.113cR |
| hoxb1b | 1127809 | 12.188cR | |||
| LHX1 | Hs.157449 | 17.58-63cM | lim1 | 577524 | 15.189cR |
| lim6 | 2155288 | 5.171cR | |||
| NOTCH3 | Hs.8546 | 19.42-45cM | notch3 | 3153196 | 3.430cR |
| notch5 | 2569969 | 3.430cR | |||
| PR65 | Hs.173902 | 19.59-98cM | fa02h04 | 5.171cR | |
| fb38a08 | 15.138cR | ||||
| CKM | Hs.118843 | 19.59-98cM | fa28d05 | 5.125cR | |
| fc14g11 | 13.183cR | ||||
| MYRL2 | Hs.9615 | 19.59-98cM | fa93e09 | 7.284cR | |
| fa97a12 | 2.340cR | ||||
| BMP2 | Hs.73853 | 20.18-27cM | bmp2 | 2804174 | 20.678cR |
| bmp2a | 2149147 | 17.43cR | |||
| SNAP25 | Hs.84389 | 20.27-37cM | snap25a | 3703097 | 20.459cR |
| snap25b | 3703099 | 17.79cR | |||
| L1CAM | Hs.1757 | X.188-198cM | nadl1.1 | 1065713 | 23.22cR |
| nadl1.2 | 1065715 | 23.163cR |
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Orthologs predicted with aid of syntenic correspondence (see Table3) are shown in bold.
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↵Position for human gene is inferred from map position of orthologous mouse gene and the mouse–human syntenic relationship (DeBry and Seldin 1996).
-
↵Genes and ESTs mapped in this study.
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↵ Hukriede et al. 1999.
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↵ Postlethwait et al. 1998, Amores et al. 1998.
-
↵ Gates et al. 1999.
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↵ Geissler et al. 1999.
