Distances from the centers of the most curved regions to the nearest starts of translation. All regions with curvature over the threshold together cover ∼1.5% of genome length. The curvature maps with window sizes of 63, 150, 250, and 400 bp were calculated. The histograms of distances from the centers of the selected regions to the nearest annotated CDS are shown. In addition, distances from randomly generated points to the CDS were calculated. The window size of 63 bp is presented by a line with circles, 150 bp by squares, 250 bp by diamonds, and 400 bp by triangles. (A) Escherichia coli K-12. The number of the most curved fragments selected is 886 for window size 63 bp, 370 for size 150 nucleotides, 220 for 250 bp, and 137 for 400 bp. (B) Haemophilus influenzae. The number of the most curved fragments selected is 357 for window size 63 bp, 143 for 150 nucleotides, 87 for 250 bp, and 59 for 400 bp.
