Curvature distributions in the neighborhood of the starts of translation. For each genome, sets of regions ±500 bases in length around the starts of translation were compiled. Only the starts of CDS longer than 125 nucleotides and flanked by upstream intergenic regions longer than 125 nucleotides were processed. The program CURVATURE with a window size equal to 150 bases was used to predict curvature distributions. The mean distributions were obtained by averaging the distributions of all fragments from the same genome. All graphs are on the same scale; for better presentation, some of them are shifted along the y axis to prevent overlapping. Major ticks on they axis correspond to the curvature of 0.02 nucleosome unit. The number of the processed CDS fragments is shown in brackets. Every 50th point is marked by a corresponding symbol: circle, diamond, square, or triangle. (A) Big mesophilic bacteria:Haemophilus influenzae, triangles up (503 CDS);Helicobacter pylori, triangles down (357 CDS);Escherichia coli, circles (1522 CDS); Bacillus subtilis, squares (1439 CDS); Synechocystis sp., triangles right (1343 CDS); Mycobacterium tuberculosis, triangles left (1078 CDS). (B) Small mesophilic bacteria: Chlamydia pneumonia, solid circles (384 CDS); Chlamydia trachomatis, open circles (326 CDS); Mycoplasma pneumoniae, open diamonds (210 CDS); Mycoplasma genitalium, solid diamonds (73 CDS); Borrelia burgdorferi, open circles (137 CDS); Rickettsia prowazekii, triangles down (342 CDS); Treponema pallidum, triangles up (176 CDS). (C) Hyperthermophilic Archaea and Bacteria: Methanococcus jannaschii, triangles down (449 CDS); Pyrococcus abyssi, open diamonds (307 CDS); Pyrococcus horikoshii, triangles up (473 CDS); Methanobacterium thermoautotrophicum, triangles left (360 CDS); Thermotoga maritima, triangles right (233 CDS); Archaeoglobus fulgidus, solid squares (374 CDS);Aquifex aeolicus, solid diamonds (242 CDS); Aeropyrum pernix, solid circles (749 CDS).
