Discovery of a Novel, Paternally Expressed Ubiquitin-specific Processing Protease Gene through Comparative Analysis of an Imprinted Region of Mouse Chromosome 7 and Human Chromosome 19q13.4

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Figure 3.
Figure 3.

Northern blot analyses of mouse and humanUSP29. (A) The expression pattern of mouseUsp29 was analyzed using poly(A)+ RNAs derived from adult tissues and different-stage embryos. A 500-bp DNA fragment corresponding to the 3′-UTR of Usp29 was used as a probe. A major transcript of mouse Usp29, 7.5 kb in length, and also two minor forms, 5.0 kb and 4.4 kb, were detected in adult brain as well as in embryos. (B) Human USP29 transcripts were detected at a low level only in the adult testis (upper). The estimated size of the transcript is about 3.5 kb. The ESTs matching sequence located in the 5′-side of PEG3 detected a 9-kb mRNA species only in ovary (lower).

This Article

  1. Genome Res. 10: 1138-1147

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