Genome-wide Detection of Allelic Imbalance Using Human SNPs and High-density DNA Arrays

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Figure 7.
Figure 7.

Allelic imbalance throughout the genome in aneuploid populations derived from high-grade dysplasia (HGD) and cancer (CA) cells. Genomic DNA was obtained from both a flow-purified aneuploid population and constitutional DNA from a gastric control biopsy for each patient. (Short black bars) Non-informative loci; (gray bars) retention of heterozygous loci; (tall black bars) SNP loci with allelic imbalance. The x-axis shows chromosome number, separated by downward tick marks. The distance between chromosomes is representational and does not equal map distance. Loci that did not pass the quality test were excluded.

This Article

  1. Genome Res. 10: 1126-1137

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