GT Repeats Are Associated with Recombination on Human Chromosome 22

Table 2.

Correlations between Recombination Intensity and Microsatellite Density

Microsatellite type R2 F1,30 P
Combined 0.23 8.80 0.0058
Tetranucleotide 0.08 2.66 0.11
Trinucelotide 0.06 1.76 0.19
Dinucleotide (all) 0.17 6.25 0.018
Dinucleotide  (non-GT) 0.006 0.19 0.67
Dinucleotide  (GT only) 0.36 17.01 0.00027
Dinucleotide  (GT, female) 0.11 3.17 0.08
Dinucleotide  (GT, male) 0.79 62.80 4 × 10−7

  • ↵This is the combined density of di-, tri-, and tetranucleotides in repeat units per million base pairs.

  • ↵Partitioning the data into male- and female-specific recombination results in loss of some data points. The reported F statistic values are F1,25 for female and F1,17 for male.

This Article

  1. Genome Res. 10: 1108-1114

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